In this article, we clearly show that conolidine, a natural analgesic alkaloid Utilized in standard Chinese medication, targets ACKR3, thereby supplying extra proof of a correlation amongst ACKR3 and soreness modulation and opening choice therapeutic avenues to the therapy of chronic agony. All logos, registered emblems and service-marks mentioned https://eugenek470cbf8.eqnextwiki.com/user