Environmental or self-antigens and homotypic interactions result in BCR and Toll-like receptor (TLR) signaling, amplifying the reaction of CLL cells to other indicators from the microenvironment and increasing the activation of anti-apoptotic and proliferation pathways.31,32 Genomic research have recognized recurrent mutations in genes regulating tumor mobile-microenvironment interact... https://howarda964szh1.eedblog.com/profile