Investigation revealed that conolidine and cannabidiol noticeably blocked Cav2.two channels. From the peripheral and central nervous process, Cav2.2 channels are located predominantly at presynaptic terminals32 and Engage in necessary roles in soreness perception by modulating depolarization-induced calcium entry into neurons33,34. Compounds that affect presynaptic Cav2.2 channel acti... https://nickx558huh5.signalwiki.com/user