These results, together with a previous report displaying that a little-molecule ACKR3 agonist CCX771 exhibits anxiolytic-like behavior in mice,2 support the principle of concentrating on ACKR3 as a singular approach to modulate the opioid method, which could open new therapeutic avenues for opioid-associated disorders. Investigation on conolidine is proscribed, https://juvenalf205fvn3.ourcodeblog.com/profile