Pentobarbital will decrease the level or effect of doravirine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. pentobarbital will decrease the level or effect of conjugated estrogens, vaginal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. pentobarbital will decrease the level or effect of bexarotene by affecting hepatic/intestinal enzyme CYP3A4... https://socialtechnet.com/story5817493/poco-conosciuto-fatti-circa-pentobarbital-natrium